Defect/deficiency in which enzyme of the urea cycle causes hyperammonemia?

The urea cycle is a metabolic pathway responsible for the detoxification of ammonia, a toxic waste product of protein metabolism, in the body. It takes place primarily in the liver and involves a series of enzymatic reactions that convert ammonia to urea, which can be excreted by the kidneys. Defects or deficiencies in any of the enzymes involved in the urea cycle can lead to hyperammonemia, a condition characterized by high levels of ammonia in the blood.

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