How erythropoiesis is regulated?

Erythropoiesis is the set of erythrocyte (red blood cell) production processes in red bone marrow from totipotent hematopoietic stem cells under the dependence of erythropoietin (EPO).

or we can say Erythropoiesis  is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell.

It is stimulated by decreased O₂ in circulation, which is detected by the kidneys, which then secrete the hormone erythropoietin. This hormone stimulates proliferation and differentiation of red cell precursors, which activates increased erythropoiesis in the hemopoietic tissues, ultimately ________ _________ _______ ____ ______ _________ _____ _______ _____ __________ _______.
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