Highlight the influence of ecological factors on toxicity of substances.

Ecological factors play a significant role in determining the toxicity of substances in the environment. Understanding these factors is crucial in assessing the potential risks posed by various pollutants and contaminants to both ecosystems and human health. Several key ecological factors can influence the toxicity of substances, including the following:

1. Species Sensitivity: Different species exhibit varying degrees of sensitivity to toxic substances. This sensitivity is influenced by factors such as physiological differences, metabolic rates, and the presence of specific detoxification mechanisms. For example, certain aquatic species like amphibians and fish are highly sensitive to waterborne pollutants due to their direct exposure to contaminants dissolved in water through their gills. In contrast, terrestrial organisms may be more affected by pollutants in the soil or air.

2. Life Stage: The toxicity of substances can vary depending on the life stage of an organism. For instance, embryos and juveniles are often more ____ ______ __________ ___ __________ ______.
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