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The Ran GTP/GDP cycle is a critical regulatory mechanism in eukaryotic cells that controls nucleocytoplasmic transport, mitotic spindle assembly, and nuclear envelope formation. Ran is a small GTP-binding protein of the Ras superfamily, existing in two states: Ran-GTP (active) and Ran-GDP ________ _____ ___ _______ _____ _______ ______ _____ _____ _____ ________ ____.
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