Question

Explain the integration of λ-phage DNA into bacterial genome

21 Jul 2024
Answer :
Word Count : 631

The integration of λ-phage (lambda phage) DNA into the bacterial genome is a critical event in the life cycle of this bacteriophage, particularly during the lysogenic phase. This process allows the phage genome to become stably incorporated into the host bacterium's chromosome, where it can be replicated and passed on to daughter cells during cell division. The integration mechanism involves a highly specific interaction between the phage genome and the bacterial genome, primarily facilitated by recombination events.

Lambda phage, a temperate bacteriophage, has two main life cycles: the lytic cycle and the lysogenic cycle. In the lytic cycle, the phage DNA replicates independently within the ___ ___ ________ ______ _________.
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