Question

Explain mismatch and recombinant repair mechanism for DNA repair.

21 Jul 2024
Answer :
Word Count : 347

Mismatch repair and recombinant repair are critical mechanisms for maintaining DNA integrity, each addressing different types of errors and damage.

Mismatch Repair (MMR):
Mismatch repair corrects errors that occur during DNA replication, such as base-base mismatches and insertion-deletion loops. These errors typically arise when the DNA polymerase incorporates an incorrect nucleotide or fails to properly align DNA strands. The MMR process involves several steps:
1. Recognition: Proteins detect the mismatch and mark the newly synthesized strand. In eukaryotes, this is done by the MutS ____ __________ ____ _________ ____ _______ _______ _________ ________ _____ ____ ___.
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