Question

Explain the integration of A-phage DNA into bacterial genome.

06 Feb 2026
Answer :
Word Count : 509
The integration of A-phage DNA into the bacterial genome occurs through a process known as site-specific recombination. This is a highly regulated mechanism that allows the phage to insert its DNA into a specific region of the host bacterial chromosome. The phage responsible for this integration is typically a temperate phage, which can either undergo a lytic cycle, where it replicates and causes the bacterial cell to lyse, or a lysogenic cycle, where the phage DNA integrates into the host genome. The first step in the integration process involves the recognition of the bacterial genome by the A-phage. The phage DNA contains specific sequences, known as the attachment site (attP), and the bacterial chromosome contains a corresponding attachment site (attB). These sequences are usually not very long ______ __________ ____ _________ _____ ___ _______ _________ ___ __________ ____ _______.
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