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The embryonic development of the cardiovascular system in chordates is a complex and highly regulated process that ensures the formation of a functional circulatory system necessary for nutrient, gas, and waste exchange. In chordates, the cardiovascular system primarily arises from the mesoderm, specifically the lateral plate mesoderm, which differentiates into the splanchnic and somatic layers. The splanchnic mesoderm gives rise to the heart and the major blood vessels, while the somatic mesoderm contributes to the _______ _________ ___ _________ ___ ____ _____ ____ __________ _________ _____ ______.
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