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The Rh antigens, particularly the D antigen, are surface proteins present on red blood cells and play a crucial role in transfusion medicine and prenatal care. The presence or absence of these antigens determines an individual's Rh blood group as either Rh-positive or Rh-negative. Clinically, Rh antigens are significant because they can trigger immune responses when an Rh-negative individual is exposed to Rh-positive blood, leading to the production of anti-D antibodies. This immune response is central to several medical conditions, including hemolytic transfusion reactions and hemolytic disease of the fetus and newborn (HDFN). In transfusion medicine, compatibility between the donor and recipient's Rh status is essential. If an Rh-negative person receives Rh-positive blood, _______ ____ ____ ____ __________ ____ _______ _______.
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