Explain Edman degradation giving the reactions involved in it. Give th

Question

Explain Edman degradation giving the reactions involved in it. Give the advantage of this method.

25 Aug 2021

Answer :

Word Count : 264

Edman degradation is a long-established technique for N-terminal sequencing of proteins and cleavage fragments. However, for accurate data analysis and amino acid assignments, Edman sequencing proceeds on samples of single proteins only and so lacks high-throughput capabilities. We describe a new method for the high-throughput determination of N-terminal sequences of multiple protein _________ __________ _________ ________ ________ _____ ________ ______ _______ ____ ________ _______.
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