Word Count : 273

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Clathrates and clathrands are two important classes of supramolecular host compounds, but they differ in their structure, mode of guest inclusion, and stability. A clathrate is an inclusion compound in which a guest molecule is physically trapped within the cavities or channels of a host crystal lattice without the formation of covalent bonds. The host framework is usually held together by weak intermolecular forces such as hydrogen bonding _________ _____ ________ ____ ________ _______ _____ ________ __________ _______.
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