Discuss various hormones involved in the regulation of the activity of

Question

Discuss various hormones involved in the regulation of the activity of pyruvate dehydrogenase.

22 Aug 2024

Answer :

Word Count : 271

Pyruvate dehydrogenase (PDH) is a crucial enzyme complex in cellular metabolism, catalyzing the conversion of pyruvate into acetyl-CoA, linking glycolysis to the citric acid cycle. The regulation of PDH activity is tightly controlled by several hormones, reflecting the metabolic state and energy needs of the organism.

1. Insulin: In response to high blood glucose levels, insulin promotes the dephosphorylation and activation of PDH. It does so by ___ _____ _________ _______ ________ __________ _________ __________ ______ __________.
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