Question

Differentiate between intrinsic and extrinsic apoptotic pathways.

22 Aug 2024
Answer :
Word Count : 319
Aspect Intrinsic Pathway Extrinsic Pathway
Trigger Activated by internal stress signals such as DNA damage, oxidative stress, or lack of growth factors. Initiated by external signals from other cells or environmental factors, primarily through death receptors on the cell surface.
Key Regulators Mitochondria, Bcl-2 family proteins (pro-apoptotic and anti-apoptotic), cytochrome c. Death receptors (e.g., _________ ______ _____ ____ ______ ___ _____ ___.
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