How BCl-2 and MCL-1 inhibitors help in cancer treatment?
Bcl-2 and Mcl-1 Inhibitors in Cancer Treatment
Bcl-2 (B-cell lymphoma 2) and Mcl-1 (myeloid cell leukemia-1) are members of the Bcl-2 family of proteins, which regulate apoptosis, the programmed cell death crucial for maintaining cellular homeostasis. In many cancers, these proteins are overexpressed, leading to resistance __________ _____ _________ ________ _______ _____ _______ _____.
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