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Size exclusion chromatography (SEC), also known as gel filtration or gel permeation chromatography, is a valuable separation technique based on the molecular size of solutes. Its preparative applications focus primarily on the isolation, purification, and fractionation of macromolecules such as proteins, polysaccharides, nucleic acids, and synthetic polymers. In preparative SEC, the stationary phase consists of __________ ____ ________ ___ ________ _____ ___.
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