Describe Rho-dependent and Rho-independent termination of transcriptio

Question

Describe Rho-dependent and Rho-independent termination of transcription.

06 Feb 2025

Answer :

Word Count : 348

Rho-dependent and Rho-independent termination are two mechanisms that regulate the cessation of transcription in bacteria, specifically during the synthesis of RNA from a DNA template.

Rho-dependent termination relies on the Rho protein, which is an ATP-dependent helicase. This process occurs when the Rho protein binds to a specific sequence on the nascent RNA, called the Rut (Rho utilization) site. As the RNA polymerase continues to transcribe, Rho binds to the Rut site and moves along the RNA in a 5' to 3' direction, powered by ATP hydrolysis. ________ _____ ______ _______ ________ _____ ___ _____ ______.
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