Chronic Myeloid Leukemia

Question

09 Feb 2021

Answer :

Word Count : 368

Chronic Myeloid Leukemia (CML) is a type of blood cancer that primarily affects older adults, making it a significant concern in clinical geriatrics. CML is characterized by the uncontrolled growth of myeloid cells, leading to an overproduction of white blood cells, particularly granulocytes. The condition typically progresses slowly and may remain asymptomatic in its early stages, which can complicate diagnosis.

The hallmark of CML is the presence of a specific genetic abnormality known as the Philadelphia chromosome (Ph chromosome), which results from a translocation between chromosomes 9 and 22. This translocation creates _______ ____ _______ _________ _________ ______ __________.
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