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Bio-cultural factors play a significant role in shaping patterns of disease in human populations by linking biological characteristics with cultural practices, environmental conditions, and social structures. Human biological diversity, including genetic variation, physiological traits, and immune responses, interacts continuously with cultural behaviors such as diet, occupation, settlement patterns, and healthcare practices, influencing susceptibility and resistance to diseases. Genetic adaptations developed in response to specific ___ ______ __________ _______ _________ __________.
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