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The synthesis of pregabalin, a pharmaceutical used primarily for neuropathic pain and epilepsy, can be approached in a manner aligned with the principles of green chemistry, focusing on atom economy, safer reagents, and reduced waste. The process typically begins with the selection of an appropriate chiral starting material, such as (S)-3-(aminomethyl)-5-methylhexanoic acid derivative, to ensure stereoselectivity and minimize the need ________ _________ _________ ________ ___ ____.
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