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Structure-Activity Relationship, commonly abbreviated as SAR, refers to the relationship between the chemical structure of a compound and its biological activity. In pharmaceutical chemistry, SAR is a fundamental concept used to understand how variations in the molecular structure of a drug influence its pharmacological effect, potency, and selectivity. It involves studying different analogs of a compound by modifying functional ____ ________ _________ ________ ___ ___ _______ ____ _______.
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