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Clathrin-coated vesicles play a crucial role in intracellular transport and membrane trafficking within the cell. They are primarily involved in the selective transport of molecules from the plasma membrane to endosomes, a process known as receptor-mediated endocytosis. These vesicles are formed when regions of the plasma membrane, enriched with specific receptors and cargo molecules, are coated on their cytoplasmic side with ________ ______ _____ _______ _____ ____ ____ ______ __________ _________.
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