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The King-Altman method is a systematic graphical approach used to analyze complex enzyme kinetics, particularly for multi-substrate or multi-step enzyme-catalyzed reactions. It provides a way to derive steady-state rate equations without directly solving complicated differential equations. In this method, each enzyme species or intermediate is represented as a node, and the rate constants of individual steps are represented as directed edges ______ _______ ________ _________ ____ ____ _____.
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