How is the enzyme, pyruvate dehydrogenase complex different from other enzymes ? How does it function in the conversion of pyruvate to acetyl-CoA?

The pyruvate dehydrogenase complex (PDC) is distinct from other enzymes because it is a multi-enzyme complex composed of three different enzymatic subunits: pyruvate dehydrogenase (E1), dihydrolipoamide transacetylase (E2), and dihydrolipoamide dehydrogenase (E3). Unlike most single enzymes that catalyze a single reaction, PDC catalyzes a sequence _________ ___ _________ ______ ______ ______ ______ _______.
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