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Nephrotic syndrome is a clinical condition characterized by massive proteinuria, hypoalbuminemia, edema, and hyperlipidemia resulting from increased permeability of the glomerular membrane. In children, the most common cause is minimal change disease, in which there is damage to the podocytes of the glomeruli. The basic pathophysiology begins with injury to the glomerular filtration barrier, which consists of the capillary _______ ________ ___ ____ _______ _______ ___.
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