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Obtain sample size for the following given information:
Explain design and analysis of data of case control study in detail.
The data on population and number of deaths for different age groups of Districts A and B in the year 2001 were collected in the following table:
| Age Group (Years) | District A | District B | ||
| Population | No. of Deaths | Population | No. of Deaths | |
| 0 - 5 | 55,300 | 385 | 51,165 | 805 |
| 5 –15 | 109,125 | 410 | 98,170 | 510 |
| 15-35 | 1,72,050 | 675 | 1,68,450 | 790 |
| 35-50 | 1,15,600 | 1625 | 1,40,625 | 990 |
| 50 & above | 2,65,775 | 3288 | 2,40,900 | 2485 |
Calculate standardised death rate by direct method, taking population of District A as the standard population.
Differentiate between complete and abridged life tables
Creatinine excretion is a parameter of kidney function. Generally speaking, lower values indicate better health. This depends on body weight. A researcher conducted a study on creatinine excretion in test group and control group to find the efficacy of a new drug. The subjects were randomly divided. He included 100 subjects in each group but for this exercise consider only 10 subjects in each group. The data obtained on creatinine level in these 10 subjects are as follows:
Test group: 16.6 19.8 17.1 17.0 15.6 20.3 24.7 18.5 17.6 22.0
Control group: 23.2 22.0 21.9 16.7 14.2 23.2 24.8 25.5 28.1 21.8
Do you think that creatinine excretion was really lower in the test group on average?
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If D+ and D ̶ denote presence and absence, respectively, of a disease and T+ and T ̶ denote test result as positive and negative, respectively, then on the basis of the following information:
| Total | |||
| 145 | 2000 | 2145 | |
| 15 | 48000 | 48015 | |
| Total | 160 | 50000 | 50160 |
Find: (i) sensitivity (ii) specificity (iii) positive and negative predictive values.