Discuss the viability of [1,3] and [1,5] hydrogen shifts on the basis of orbital symmetry and geometry consideration

Using FMO model, explain why in thermal condition disrotatory motion would necessary for cyclisation of 1,3,5- hexatriene and conrotatory for 2,4-hexadiene

Complete the following reactions:

Cycloaddition reaction of carbene generated by the photolysis of diazo methane in inert gas with cis-2-butene is not stereospecific. Explain with the help of steps involved in the reaction

Give the mechanism of the following reactions: 

i) Perkin condensation

ii) Michael addition

iii) Wolff – Kishner reduction

How would you convert the following:

i) Haptanal to Haptane

ii) 2–Cyclohexanone to 2-Cyclohexanol

iii) 3-Heptyne to trans-3-Heptene

Isotope effect is absent in E1 elimination

E2 elimination is an anti elimination

E1 elimination does not follow saytzeff rule.

E2 elimination does not give rearranged product

In aldol condensation aldehyde must contain an  -hydrogen atom.

In Wittig reaction, the methyl, primary and secondary alkyl halide used to prepare Witting reagent(ylide) but not tertiary.

Aromalic aldehydes are less reactive than aliphatic aldehyde.

Alkenes are readily hydroxylated.

Low molecular-weight ozonides cannot be isolated easily

For Diels-Alder reaction, a diene must be able to adopt a cis geometry.

Differentiate between the SN2 and SNAr2 mechanisms of reactions

Which one in the following pairs is more stable and why? Explain the factors responsible for this.

i) (CH3)2CH 2 and (CH3)3CH+

ii) (C6H5)2CH +  and CH2 = CH – CH 2

What is primary isotope effect? How is it different from the secondary isotope effect? Explain with the help of an example of electrophilic substitution in aromatic compound

Draw and explain the potential energy diagram for the reaction,

i) When step 1 is the rate determining step.

ii) When step 2 is the rate determining step.