IGNOU BBCCT 127 SOLVED ASSIGNMENT

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BBCCT 127 2025 - English

ASSIGNMENT

Immunology

Core Course in Biochemistry

Course Code: BBCCT-127

Assignment Code: BBCCT-127/TMA/2025

Maximum Marks: 100

Note: Attempt all questions. The marks for each question are indicated against it. Write all answers in your own words; do not copy from the course material.

PART-(A)

1. Give an overview of primary and secondary lymphoid organ in adult man.

2. Write short note on the followings:

a) Anatomical and Physiological barrier of Innate Immunity

b) Types of Antigen

3. What are the biological consequences of complement activation.

4. Differentiate between:

a) Isotype and Allotype Determinants

b) Immunoglobulin A and Immunoglobulin E

5. Enumerate Tonegawa and Hozumi Experiment of Two gene model.

PART-(B)

6. Explain B- cell development with a schematic representation.

7. Write short note on the following:

a) Endogenous pathway of antigen presentation

b) Positive T-cell Selection

8. a) Compare NK and NKT cells.

b) Describe mechanism of B-cell tolerance

9. Differentiate between the following:

i) Autograft and Xenograft

ii) Recombinant vaccines and Whole organism as vaccines

10. Give an overview of Type IV hypersensitivity.

BBCCT 127 (January 2026 - July 2026) - ENGLISH

ASSIGNMENT

Immunology

Core Course in Biochemistry

Course Code: BBCCT-127

Assignment Code: BBCCT-127/TMA/2026

Maximum Marks: 100

Note: Attempt all questions. The marks for each question are indicated against it. Write all answers in your own words; do not copy from the course material.

PART-(A)

1. Give an overview of cells of immune system.

2 a) How pathogen is internalised?

b) Describe the traits of Immunogen

3. Explain the classical pathway of complement activation.

4. Differentiate between:

a) Idiotype and Allotype Determinants

b) Immunoglobulin G and Immunoglobulin M

5. Enumerate Dreyer-Bennett Hypothesis.

PART-(B)

6. Explain three important B- cell differentiation events.

7. Write short note on the following:

a) Structure of MHC

b) CD8 Cytotoxic T-cells

8. Give an overview of T-cell development with a schematic representation.

9. Differentiate between the following:

i) Central tolerance and Peripheral tolerance

ii) DNA vaccines and Purified Macromolecules as Vaccines

10. Give an overview of Type III hypersensitivity.

BBCCT 127 2025 - Hindi

बी.एससी.ऑनर्स जैव-रसायन

सत्रीय कार्य

प्रतिरक्षा विज्ञान

कोर्स कोडः बीबीसीसीटी-127

सत्रीय कार्य कोडः बीबीसीसीटी-/127 टीएमए/2025

अधिकतम अंकः 100

नोटः सभी प्रश्नों को हल करें। प्रत्येक प्रश्न के अंक उसके सम्मुख अंकित हैं। सभी उत्तर अपने शब्दों में लिखें। पाठ्यक्रम सामग्री से नकल न करें।

भाग- (क)

1 व्यस्क व्यक्ति में प्राथमिक और द्वितीयक लिम्फोइड अंगों का अवलोकन दीजिये।

2 निम्नलिखित पर संक्षिप्त नोट लिखें।

क) जन्मजात प्रतिरक्षा के संरचनात्मक तथा शरीर क्रियात्मक अवरोधक ।

ख) एन्टीजन के प्रकार।

3 पूरक सक्रियण के जैविक परिणाम क्या है?

4 निम्नलिखित के बीच में अंतर करें :

क) आइसोटाइप और एलोटाइप निर्धारक

ख) इम्युनोग्लोबुलिन ए इम्युनोग्लोबुलिन इ

5 दो जीन मॉडल के टोनोगावा एवं होजूमी परीक्षण के बारे में लिखें।

भाग- (ख)

6 बी-कोशिकाओं के विकास को योजनाबद्ध निरूपण के साथ समझाइए।

7 निम्नलिखित पर संक्षिप्त नोट लिखें :

क) एन्टीजन प्रस्तुति का अंतर्जात मार्ग / पथ

ख) पाजीटिव / सकारात्मक टी-कोशिका चयन

8 क) NK तथा NKT कोशिकाओं की तुलना करें।

ख) बी-कोशिका सहनशीलता की कार्यविधि का वर्णन करें।

9 निम्नलिखित के बीच अंतर करें:

क) आटोग्राफ्ट और जेनोग्राफ्ट

ख) पुनर्योगज टीके और पूर्ण जीव टीके के रूप में।

10 अतिसंवेदनशीलता के प्रकार IV का अवलोकन दीजिये।

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Course Name	B.Sc. Honours in Biochemistry
Course Code	BSCBCH
Programm	Courses
Language	English

 

 

 

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