Yeast two-hybrid system

The yeast two-hybrid system (Y2H) is a molecular biology technique used to study protein-protein interactions. It exploits the ability of the Saccharomyces cerevisiae (baker's yeast) to be genetically manipulated, allowing researchers to investigate interactions between two proteins in a living cell. The method is based on the principle that the transcription of a reporter gene can be activated when ______ _______ _____ ________ ______ __________ _________ _________ _____ ____ _____ ____.
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