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The sodium-potassium pump is an essential bioinorganic system responsible for maintaining the electrochemical gradient across cell membranes, which is crucial for nerve impulse transmission and muscle contraction. It is an example of an organometallic-type enzyme mechanism, where ATP acts as a cofactor and the protein contains metal-binding sites that facilitate conformational changes. The pump actively transports three sodium ions (Na⁺) out of the cell and two ___ __________ ___ ____ _________ ______ _______ _______ ______ __________ ___.
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