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Maternal determinants are molecules such as mRNAs, proteins, and transcription factors deposited into the egg cytoplasm by the mother during oogenesis. These substances are inherited by the zygote and guide the earliest stages of embryonic development before the activation of the zygotic genome. They establish spatial organization within the embryo and initiate key developmental pathways that determine cell fate and _______ _______ _________ _________ _________ _____ _______ ________ _____ _______ ___.
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