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The clinical evaluation of a drug in human beings is a critical process that ensures the safety, efficacy, and optimal dosing of a new pharmaceutical agent. This evaluation is carried out in a structured series of phases known as Phase I, Phase II, Phase III, and sometimes Phase IV. Phase I is the initial stage of testing in humans, where the primary goal is to assess the safety, ______ _______ ______ ______ ________ _____ ______ _______ ________ ________.
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