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Substance abuse plays a significant role in the spread of HIV/AIDS by influencing both behavior and biological susceptibility. Individuals who use substances such as alcohol, opioids, and stimulants often engage in high-risk behaviors, including unprotected sexual activity and sharing of contaminated needles, which are primary modes of HIV transmission. Intravenous drug users are particularly vulnerable because the virus can be ________ ____ ____ ___ ____ ___ ______ _______ ________ ___ __________ _______.
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