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The prothoracic gland plays a central role in regulating insect metamorphosis by synthesizing and secreting ecdysteroid hormones, mainly ecdysone, which control molting and developmental transitions. This paired endocrine gland is typically located in the thoracic region of larval insects and is most active during larval and pupal stages. Its activity ___ ______ _______ ____ ______ ______.
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