Role of genetics in Drug Resistance.
In the realm of HIV infection, drug resistance is a significant concern, particularly as it pertains to the effectiveness of antiretroviral therapy (ART). While several factors contribute to drug resistance, including patient adherence to medication regimens and the potency of the drugs themselves, genetics plays a crucial role in determining an individual's susceptibility to developing resistance.
Genetic factors influence drug resistance primarily through two mechanisms: viral genetic variation and _____ ____ __________ _____ _______ ____ __________ __________ _____ ______ ______.
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