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Necrosis is a form of cell injury that results in the premature death of cells in living tissue. Unlike apoptosis, which is a programmed and controlled process, necrosis occurs in an uncontrolled manner and usually triggers an inflammatory response in the surrounding tissue. It can be caused by various factors, including physical damage, chemical exposure, toxins, infection, or interruption of blood supply leading to ischemia. At the cellular level, necrosis is characterized by a series _________ ___ ______ ____ _________ ____ __________ _______ _______.
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