Name the enzyme whose deficiency causes homocystinuria

Enzymes  deficiency causes beriberi neuropathy as well as a peripheral neuropathy and polyneuritis that leads to paralysis of the eye muscles, loss of muscular coordination, and memory loss, especially in long-term alcoholics. Inadequate niacin intake causes pellagra, with symptoms that include intellectual ____ __________ ________ ______ _____ _________ ___ _____ __________ __________ __________ _________.
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