Give glutamate dehydrogenase reaction (GDH Reaction).

Question

24 Apr 2023

Answer :

Word Count : 279

Glutamate dehydrogenase (GDH) is an enzyme that catalyzes the reversible conversion of glutamate and α-ketoglutarate into ammonia and NADH (or NADPH). This reaction plays an important role in cellular metabolism, particularly in the liver and kidneys, where it participates in the regulation of the urea cycle and the detoxification of ammonia.

The GDH reaction can be written as follows:

L-glutamate + α-ketoglutarate + NAD(P)H + H+ ⇌ 2-oxoglutarate + ________ ____ ____ _______ _________ __________ ____ _____ _______.
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