Give a brief account of the secondary lymphoid organs of the Immune System.

Secondary lymphoid organs play a crucial role in the immune system by providing an environment for immune cells to interact, respond to pathogens, and initiate adaptive immune responses. These organs are the sites where immune cells are activated and differentiate in response to antigens. They include the lymph nodes, spleen, mucosal-associated lymphoid tissues (MALT), and other lymphoid structures.

Lymph nodes are the most well-known secondary lymphoid organs. They are distributed throughout the body along lymphatic vessels and serve as filtering stations for lymph fluid. Each lymph node consists of a capsule, cortex, and medulla. The cortex contains follicles, which are rich in B cells, and the paracortex, where T cells are located. The medulla consists of macrophages and plasma cells. Lymph nodes act as sites for antigen ____ ____ _________ ________ ______.
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