Explain the unique features of size exclusion chromatography.

Size exclusion chromatography (SEC), also known as gel filtration chromatography, is a chromatographic technique used to separate molecules based on their size. Unlike other chromatographic methods that separate based on chemical affinity or charge, SEC relies solely on the molecular size, making it ideal for separating large biomolecules, such as proteins, nucleic acids, and polysaccharides, from smaller ones.

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