Explain the term Buerger’s disease. Also, enlist other harmful effects of smoking on health

Buerger's disease, also known as thromboangiitis obliterans, is a rare and severe condition that primarily affects the blood vessels in the arms and legs. This disease is characterized by the inflammation and clotting of small and medium-sized arteries and veins, leading to reduced blood flow to the affected limbs. While the exact cause of Buerger's disease remains unclear, it is strongly associated with tobacco use, particularly cigarette smoking. It is rarely observed in individuals who do not smoke.

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