Question

Explain the replication cycle of polio virus with suitable diagram.

21 Jul 2024
Answer :
Word Count : 448

The replication cycle of the poliovirus is a well-orchestrated series of steps that takes place inside the host cell, ultimately leading to the production of new viral particles. Here’s a step-by-step explanation:

1. Attachment: The poliovirus begins its infection process by attaching to specific receptors on the surface of a susceptible host cell. The primary receptor for poliovirus is the CD155 (PVR) on the host cell's membrane.

2. Entry: After attachment, the virus enters the cell through a process called endocytosis. The virus is engulfed into a vesicle, which then fuses with the endosomal membrane, releasing the viral RNA into the cytoplasm of the host cell.

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