Question

Explain the neurochemical process and higher cerebral functions.

27 Aug 2021
Answer :
Word Count : 1004

Various neurochemichal process are as follows :

1.Acetylcholine (Ach)
Cholinergic mechanisms are important in wakefulness and cortical activation.
In general, increased acetylcholine is associated with wakefulness and REM sleep
and decreased level of acetylcholine promotes sleep and non-REM sleep
phenomena.

2.Noradrenaline
Increased level of noradrenalin is implicated in wakefulness. Locus coeruleus
noradrenergic neurons decrease their rate of firing at sleep onset. Drugs that
diminish noradrenergic neurotransmission tend to cause sedation, while the
reverse is the case for drugs that potentiate noradrenergic function.25 Consciousness and NeuroChemical Process and Higher Cerebral Functions

3.Serotonin
Serotonin complements the action of noradrenalin and acetylcholine in promoting
wakefulness and cortical responsiveness. Experiments provide evidence that the
level of serotonin during waking is higher in most cortical and subcortical areas
than during sleep.
The seretonergic neurons in the raphe nuclei show the highest firing rate during
waking decrease their firing rate during slow wave sleep.
4. Dopamine
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