Explain the following with respect to TCA cycle:

i) Substrate chanelling

ii) anaplerosis

In the context of the TCA cycle (Tricarboxylic Acid Cycle), substrate channeling refers to the direct transfer of metabolites between enzymes in a metabolic pathway without them diffusing freely in the surrounding medium. This efficient process _______ ___ ____ _________ _______ ___ ______ ____ ________ _________.
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