Explain the following disorders of amino acid metabolism:
a) Homocystinuria
b) Hartnup disease
a) Homocystinuria:
Homocystinuria is a genetic disorder caused by a deficiency of the enzyme cystathionine β-synthase, which is involved in the conversion of homocysteine to cystathionine in the methionine metabolism pathway. This leads to an accumulation of homocysteine and its metabolites _______ ____ _____ _______ ________ ____.
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