Question

Discuss the mechanisms involved in gene silencing by RNA interference.

27 Jan 2024
Answer :
Word Count : 370

RNA interference (RNAi) is a powerful mechanism that cells use to regulate gene expression by silencing specific genes. Here's how it works:

  1. Generation of small interfering RNA (siRNA) or microRNA (miRNA):

    • RNAi begins with the generation of small RNA molecules called siRNAs or miRNAs.
    • In the case of siRNAs, they are typically introduced into the cell exogenously or are generated from long double-stranded RNA molecules through the action of an enzyme called Dicer.
    • miRNAs, on the other hand, are transcribed from specific genes within the cell and then processed _________ ________ ______ _______ ___ _______ ___ ______ _____ ___.
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