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The genetic code consists of 64 codons, of which 61 specify amino acids, but most cells contain far fewer than 61 distinct tRNAs. This efficiency is made possible by wobble base pairing, a mechanism that allows a single tRNA to recognize multiple codons coding for the same amino acid. According to Crick’s wobble hypothesis, strict Watson–Crick base pairing occurs between the first two bases of the _______ _________ __________ ______ _______ _____ ___ ______.
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