Discuss different cytokines that act as mediators of innate and adaptive immune systems.
Cytokines are small proteins secreted by various cells in the immune system that act as mediators of both the innate and adaptive immune responses. These signaling molecules play crucial roles in coordinating and regulating immune cell communication and function. Here, we'll delve into some of the key cytokines involved in both arms of the immune system:
Innate Immune System:
1. Interleukin-1 (IL-1): Produced mainly by macrophages, IL-1 is a potent pro-inflammatory cytokine that helps initiate and amplify innate immune responses. It induces fever, promotes inflammation by activating endothelial cells, and enhances the expression of adhesion molecules. IL-1 also stimulates the production of other cytokines, such as IL-6 and TNF-alpha.
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