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Diphtheria is an acute bacterial infection caused by *Corynebacterium diphtheriae*, primarily affecting the upper respiratory tract and occasionally the skin. It is a highly contagious disease transmitted through respiratory droplets from coughing or sneezing of an infected person. The bacterium produces a potent exotoxin responsible for the characteristic clinical manifestations and systemic ____ ____ _________ _____ __________ ______ ________ ____ ______ ____.
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