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Transcription by RNA polymerase II is a highly regulated process responsible for synthesizing messenger RNA in eukaryotic cells. It begins at specific DNA sequences known as core promoters, which are typically located upstream of the transcription start site. The core promoter contains conserved elements such as the TATA box, initiator (Inr) sequence, TFIIB recognition element (BRE), and downstream promoter element (DPE). __________ ________ _____ _________ ____ _____.
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