Describe the role of pyruvate dehydrogenase enzyme complex in acetyl CoA synthesis.
Pyruvate dehydrogenase (PDH) is a crucial enzyme complex in the metabolism of carbohydrates and lipids, serving as a bridge between glycolysis and the citric acid cycle (Krebs cycle). This multi-enzyme complex facilitates the conversion of pyruvate, the end product of glycolysis, into acetyl CoA, ___ _________ ______ _________ _______ ________ __________.
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